Machine learning models for rat multigeneration reproductive toxicity prediction

Machine learning models for rat multigeneration reproductive toxicity prediction

Reproductive toxicity is one of the prominent endpoints in the risk assessment of environmental and industrial chemicals. Due to the complexity of the reproductive system, traditional reproductive toxicity testing in animals, especially guideline multigeneration reproductive toxicity studies, take a...

Full description

Bibliographic Details
Main Authors: Jie Liu, Wenjing Guo, Fan Dong, Jason Aungst, Suzanne Fitzpatrick, Tucker A. Patterson, Huixiao Hong
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Pharmacology
Subjects:
multigeneration reproductive toxicity
machine learning
molecular descriptor
consensus model
toxicity prediction
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.1018226/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.1018226/full

Similar Items