Maternal and Infant Histo-Blood Group Antigen (HBGA) Profiles and Their Influence on Oral Rotavirus Vaccine (Rotarix<sup>TM</sup>) Immunogenicity among Infants in Zambia

Maternal and Infant Histo-Blood Group Antigen (HBGA) Profiles and Their Influence on Oral Rotavirus Vaccine (Rotarix<sup>TM</sup>) Immunogenicity among Infants in Zambia

Live-attenuated, oral rotavirus vaccines have significantly reduced rotavirus-associated diarrhoea morbidity and infant mortality. However, vaccine immunogenicity is diminished in low-income countries. We investigated whether maternal and infant intrinsic susceptibility to rotavirus infection via hi...

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Bibliographic Details
Main Authors: Adriace Chauwa, Samuel Bosomprah, Natasha Makabilo Laban, Bernard Phiri, Mwelwa Chibuye, Obvious Nchimunya Chilyabanyama, Sody Munsaka, Michelo Simuyandi, Innocent Mwape, Cynthia Mubanga, Masuzyo Chirwa Chobe, Caroline Chisenga, Roma Chilengi
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Vaccines
Subjects:
rotavirus
vaccines
histo-blood groups
immunogenicity
Zambia
Online Access:https://www.mdpi.com/2076-393X/11/8/1303

Internet

https://www.mdpi.com/2076-393X/11/8/1303

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