Effective, broad spectrum control of virulent bacterial infections using cationic DNA liposome complexes combined with bacterial antigens.

Protection against virulent pathogens that cause acute, fatal disease is often hampered by development of microbial resistance to traditional chemotherapeutics. Further, most successful pathogens possess an array of immune evasion strategies to avoid detection and elimination by the host. Developmen...

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Bibliographic Details
Main Authors: Robin Ireland, Norma Olivares-Zavaleta, Jonathan M Warawa, Frank C Gherardini, Clayton Jarrett, B Joseph Hinnebusch, John T Belisle, Jeffery Fairman, Catharine M Bosio
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-05-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2877747?pdf=render