A Specific Host/Microbial Signature of Plasma-Derived Extracellular Vesicles Is Associated to Thrombosis and Marrow Fibrosis in Polycythemia Vera

A Specific Host/Microbial Signature of Plasma-Derived Extracellular Vesicles Is Associated to Thrombosis and Marrow Fibrosis in Polycythemia Vera

Polycythemia vera is a myeloproliferative neoplasm with increased risk of thrombosis and progression to myelofibrosis. However, no disease-specific risk factors have been identified so far. Circulating extracellular vesicles (EVs) are mostly of megakaryocyte (MK-EVs) and platelet (PLT-EVs) origin an...

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Bibliographic Details
Main Authors: Martina Barone, Monica Barone, Francesca Ricci, Giuseppe Auteri, Francesco Fabbri, Erika Bandini, Francesco Francia, Pier Luigi Tazzari, Nicola Vianelli, Silvia Turroni, Michele Cavo, Lucia Catani, Marco Candela, Francesca Palandri
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Cancers
Subjects:
polycythemia vera
extracellular vesicles
microbial DNA cargo
biomarker
thrombosis
marrow fibrosis
Online Access:https://www.mdpi.com/2072-6694/13/19/4968

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https://www.mdpi.com/2072-6694/13/19/4968

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