Stereoselective Synthesis of 1-Substituted Homotropanones, including Natural Alkaloid (−)-Adaline

The stereocontrolled synthesis of 1-substituted homotropanones, using chiral <i>N</i>-<i>tert</i>-butanesulfinyl imines as reaction intermediates, is described. The reaction of organolithium and Grignard reagents with hydroxy Weinreb amides, chemoselective <i>N</i>...

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Bibliographic Details
Main Authors: Sandra Hernández-Ibáñez, Ana Sirvent, Miguel Yus, Francisco Foubelo
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/28/5/2414