Stereoselective Synthesis of 1-Substituted Homotropanones, including Natural Alkaloid (−)-Adaline

The stereocontrolled synthesis of 1-substituted homotropanones, using chiral <i>N</i>-<i>tert</i>-butanesulfinyl imines as reaction intermediates, is described. The reaction of organolithium and Grignard reagents with hydroxy Weinreb amides, chemoselective <i>N</i>...

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Hlavní autoři: Sandra Hernández-Ibáñez, Ana Sirvent, Miguel Yus, Francisco Foubelo
Médium: Článek
Jazyk:English
Vydáno: MDPI AG 2023-03-01
Edice:Molecules
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On-line přístup:https://www.mdpi.com/1420-3049/28/5/2414