Tumor-Associated Macrophages/Microglia in Glioblastoma Oncolytic Virotherapy: A Double-Edged Sword

Tumor-Associated Macrophages/Microglia in Glioblastoma Oncolytic Virotherapy: A Double-Edged Sword

Oncolytic virotherapy is a rapidly progressing field that uses oncolytic viruses (OVs) to selectively infect malignant cells and cause an antitumor response through direct oncolysis and stimulation of the immune system. Despite demonstrated pre-clinical efficacy of OVs in many cancer types and some...

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Bibliographic Details
Main Authors: Sarah E. Blitz, Ari D. Kappel, Florian A. Gessler, Neil V. Klinger, Omar Arnaout, Yi Lu, Pier Paolo Peruzzi, Timothy R. Smith, Ennio A. Chiocca, Gregory K. Friedman, Joshua D. Bernstock
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:International Journal of Molecular Sciences
Subjects:
tumor-associated macrophages/microglia (TAMs)
oncolytic virotherapy
tumor microenvironment
glioblastoma (GBM)
Online Access:https://www.mdpi.com/1422-0067/23/3/1808

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https://www.mdpi.com/1422-0067/23/3/1808

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