Multiplexed quantification of insulin and C-peptide by LC-MS/MS without the use of antibodies

Introduction: The measurement of insulin and C-peptide provides a valuable tool for the clinical evaluation of hypoglycemia. In research, these biomarkers are used together to better understand hyperinsulinemia, hepatic insulin clearance, and beta cell function. Liquid chromatography-tandem mass spe...

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Bibliographic Details
Main Authors: North Foulon, Elisha Goonatilleke, Michael J. MacCoss, Michelle A. Emrick, Andrew N. Hoofnagle
Format: Article
Language:English
Published: Elsevier 2022-08-01
Series:Journal of Mass Spectrometry and Advances in the Clinical Lab
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2667145X22000189