A rapid and reference-free imputation method for low-cost genotyping platforms

Abstract Most current genotype imputation methods are reference-based, which posed several challenges to users, such as high computational costs and reference panel inaccessibility. Thus, deep learning models are expected to create reference-free imputation methods performing with higher accuracy an...

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Bibliographic Details
Main Authors: Vinh Chi Duong, Giang Minh Vu, Thien Khac Nguyen, Hung Tran The Nguyen, Thang Luong Pham, Nam S. Vo, Tham Hong Hoang
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-50086-4