A Biomedical Case Study Showing That Tuning Random Forests Can Fundamentally Change the Interpretation of Supervised Data Structure Exploration Aimed at Knowledge Discovery

Knowledge discovery in biomedical data using supervised methods assumes that the data contain structure relevant to the class structure if a classifier can be trained to assign a case to the correct class better than by guessing. In this setting, acceptance or rejection of a scientific hypothesis ma...

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Bibliographic Details
Main Authors: Jörn Lötsch, Benjamin Mayer
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:BioMedInformatics
Subjects:
Online Access:https://www.mdpi.com/2673-7426/2/4/34