Existing Evidence for the Repurposing of PARP-1 Inhibitors in Rare Demyelinating Diseases

Over the past decade, Poly (ADP-ribose) polymerase-1 (PARP-1) inhibitors have arisen as a novel and promising targeted therapy for breast cancer gene (BRCA)-mutated ovarian and breast cancer patients. Therapies targeting the enzyme, PARP-1, have since established their place as maintenance drugs for...

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Bibliographic Details
Main Authors: Marianna Mekhaeil, Kumlesh Kumar Dev, Melissa Jane Conroy
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/14/3/687