Accelerated immunosenescence in rheumatoid arthritis: impact on clinical progression
Abstract Patients with rheumatoid arthritis (RA) develop features of accelerated ageing, including immunosenescence. These changes include decreased thymic functionality, expansion of late-differentiated effector T cells, increased telomeric attrition, and excessive production of cytokines (senescen...
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| Format: | Article |
| Language: | English |
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BMC
2020-03-01
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| Series: | Immunity & Ageing |
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| Online Access: | http://link.springer.com/article/10.1186/s12979-020-00178-w |