Nerve Targeting via Myelin Protein Zero and the Impact of Dimerization on Binding Affinity

Nerve Targeting via Myelin Protein Zero and the Impact of Dimerization on Binding Affinity

Background: Surgically induced nerve damage is a common but debilitating side effect. By developing tracers that specifically target the most abundant protein in peripheral myelin, namely myelin protein zero (P0), we intend to support fluorescence-guided nerve-sparing surgery. To that end, we aimed...

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Bibliographic Details
Main Authors: Nataliia Berehova, Tessa Buckle, Maarten P. van Meerbeek, Anton Bunschoten, Aldrik H. Velders, Fijs W. B. van Leeuwen
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Molecules
Subjects:
fluorescence imaging
nerve targeting
myelin protein zero
fluorescence-guided surgery
Online Access:https://www.mdpi.com/1420-3049/27/24/9015

Internet

https://www.mdpi.com/1420-3049/27/24/9015

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