HLA Class I Expression Is Associated with DNA Damage and Immune Cell Infiltration into Dysplastic and Neoplastic Lesions in Ulcerative Colitis

HLA Class I Expression Is Associated with DNA Damage and Immune Cell Infiltration into Dysplastic and Neoplastic Lesions in Ulcerative Colitis

Human leukocyte antigen class I (HLA-I) is considered a genetic pathogen for ulcerative colitis (UC). This study aimed to investigate the significance of DNA damage and HLA-I expression in infiltrating immune cells and immune checkpoint protein PD-L1 expression in dysplasia/colitic cancer (CC) and s...

Full description

Bibliographic Details
Main Authors: Haruka Okami, Naoya Ozawa, Makoto Sohda, Takehiko Yokobori, Katsuya Osone, Bilguun Erkhem-Ochir, Gendensuren Dorjkhorloo, Takuya Shiraishi, Takuhisa Okada, Akihiko Sano, Makoto Sakai, Tatsuya Miyazaki, Hiroomi Ogawa, Takashi Yao, Takahiro Oike, Hiro Sato, Ken Shirabe, Atsushi Shibata, Hiroshi Saeki
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:International Journal of Molecular Sciences
Subjects:
human leukocyte antigen
DNA damage
colitic cancer
immune cells
Online Access:https://www.mdpi.com/1422-0067/24/17/13648

Internet

https://www.mdpi.com/1422-0067/24/17/13648

Similar Items