PgtE Enzyme of Salmonella enterica Shares the Similar Biological Roles to Plasminogen Activator (Pla) in Interacting With DEC-205 (CD205), and Enhancing Host Dissemination and Infectivity by Yersinia pestis

Yersinia pestis, the cause of plague, is a newly evolved Gram-negative bacterium. Through the acquisition of the plasminogen activator (Pla), Y. pestis gained the means to rapidly disseminate throughout its mammalian hosts. It was suggested that Y. pestis utilizes Pla to interact with the DEC-205 (C...

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Main Authors: Qiao Li, Chenglin Ye, Fei Zhao, Wenjin Li, Sizhe Zhu, Yin Lv, Chae Gyu Park, Yingmiao Zhang, Ling-Yu Jiang, Kun Yang, Yingxia He, Huahua Cai, Song Zhang, Hong-Hui Ding, Olivia Adhiambo Njiri, John Mambwe Tembo, Ayman Ahmad Alkraiem, An-Yi Li, Zi-Yong Sun, Wei Li, Mei-Ying Yan, Biao Kan, Xixiang Huo, John D. Klena, Mikael Skurnik, Andrey P. Anisimov, Xiaofang Gao, Yanping Han, Rui-Fu Yang, Xiding Xiamu, Yuanzhi Wang, Hongxiang Chen, Bao Chai, Yicheng Sun, Jingping Yuan, Tie Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.791799/full