Highly efficient manipulation of nervous system gene expression with NEPTUNE
Summary: Genetic loss and gain of function in mice have typically been studied by using knockout or knockin mice that take months to years to generate. To address this problem for the nervous system, we developed NEPTUNE (NEural Plate Targeting by in Utero NanoinjEction) to rapidly and flexibly tran...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-08-01
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Series: | Cell Reports: Methods |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2667237521000886 |