Targeting cytotoxic lymphocyte antigen 4 (CTLA-4) in breast cancer

Abstract Breast cancer (BC) has a high mortality rate and is one of the most common malignancies in the world. Initially, BC was considered non-immunogenic, but a paradigm shift occurred with the discovery of tumor-infiltrating lymphocytes (TILs) and regulatory T cells (Tregs) in the BC tumor microe...

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Bibliographic Details
Main Authors: Maryam Jama, Yasser Tabana, Khaled H. Barakat
Format: Article
Language:English
Published: BMC 2024-07-01
Series:European Journal of Medical Research
Online Access:https://doi.org/10.1186/s40001-024-01901-9