Combination Therapy Is Superior to Sequential Monotherapy for the Initial Treatment of Hypertension: A Double‐Blind Randomized Controlled Trial

Combination Therapy Is Superior to Sequential Monotherapy for the Initial Treatment of Hypertension: A Double‐Blind Randomized Controlled Trial

BackgroundGuidelines for hypertension vary in their preference for initial combination therapy or initial monotherapy, stratified by patient profile; therefore, we compared the efficacy and tolerability of these approaches. Methods and ResultsWe performed a 1‐year, double‐blind, randomized controlle...

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Bibliographic Details
Main Authors: Thomas M. MacDonald, Bryan Williams, David J. Webb, Steve Morant, Mark Caulfield, J. Kennedy Cruickshank, Ian Ford, Peter Sever, Isla S. Mackenzie, Sandosh Padmanabhan, Gerald P. McCann, Jackie Salsbury, Gordon McInnes, Morris J. Brown
Format: Article
Language:English
Published: Wiley 2017-11-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
angiotensin II receptor blocker
comparative effectiveness
diuretics
renin
treatment effectiveness
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.117.006986

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.117.006986

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