Integrated Analysis Reveals the Gut Microbial Metabolite TMAO Promotes Inflammatory Hepatocellular Carcinoma by Upregulating POSTN

Integrated Analysis Reveals the Gut Microbial Metabolite TMAO Promotes Inflammatory Hepatocellular Carcinoma by Upregulating POSTN

Liver cancer has a high mortality rate. Chronic inflammation is one of the leading causes of hepatocellular carcinoma. Recent studies suggested high levels of trimethylamine N-oxide (TMAO) may correlate with increased risk of inflammatory-induced liver cancer. However, the mechanisms by which TMAO p...

Full description

Bibliographic Details
Main Authors: Yonglin Wu, Xingyu Rong, Miaomiao Pan, Tongyao Wang, Hao Yang, Xiejiu Chen, Zhenming Xiao, Chao Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
microbial metabolite
TMAO
inflammatory
hepatocellular carcinoma
RNA-seq
database reanalysis
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.840171/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2022.840171/full

Similar Items