Sodium butyrate mediates histone crotonylation and alleviated neonatal rats hypoxic–ischemic brain injury through gut–brain axis

Sodium butyrate mediates histone crotonylation and alleviated neonatal rats hypoxic–ischemic brain injury through gut–brain axis

Neonatal hypoxic–ischemic encephalopathy (HIE) refers to nervous system damage caused by perinatal hypoxia, which is the major cause of long-term neuro-developmental disorders in surviving infants. However, the mechanisms still require further investigation. In this study, we found that the butanoat...

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Bibliographic Details
Main Authors: Xuejia He, Ting Zhang, Yubing Zeng, Pei Pei, Yulan Liu, Wenbin Jia, Hongyang Zhao, Meirong Bi, Shan Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Microbiology
Subjects:
neonatal hypoxic–ischemic encephalopathy
hypoxic–ischemic brain damage
gut microbiota
sodium butyrate
histone crotonylation
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.993146/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2022.993146/full

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