Evolution of Bacterial Persistence to Antibiotics during a 50,000-Generation Experiment in an Antibiotic-Free Environment
Failure of antibiotic therapies causes > 700,000 deaths yearly and involves both bacterial resistance and persistence. Persistence results in the relapse of infections by producing a tiny fraction of pathogen survivors that stay dormant during antibiotic exposure. From an evolutionary perspective...
Main Authors: | Hugo Mathé-Hubert, Rafika Amia, Mikaël Martin, Joël Gaffé, Dominique Schneider |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-03-01
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Series: | Antibiotics |
Subjects: | |
Online Access: | https://www.mdpi.com/2079-6382/11/4/451 |
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