Developmental mechanism of the periodic membrane skeleton in axons

Actin, spectrin, and associated molecules form a periodic sub-membrane lattice structure in axons. How this membrane skeleton is developed and why it preferentially forms in axons are unknown. Here, we studied the developmental mechanism of this lattice structure. We found that this structure emerge...

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Bibliographic Details
Main Authors: Guisheng Zhong, Jiang He, Ruobo Zhou, Damaris Lorenzo, Hazen P Babcock, Vann Bennett, Xiaowei Zhuang
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-12-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/04581