Regulation of tumorigenic splicing by protein condensates with specific biophysical properties

The role of biophysical properties of protein condensates in regulating gene expression and tumorigenesis remains unclear. We recently discovered that A-kinase anchoring protein 8 (AKAP8, also known as AKAP95), a RNA splicing regulator, supports tumorigenesis by forming liquid-like condensates, and...

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Bibliographic Details
Main Authors: Wei Li, Hao Jiang
Format: Article
Language:English
Published: Taylor & Francis Group 2020-11-01
Series:Molecular & Cellular Oncology
Subjects:
Online Access:http://dx.doi.org/10.1080/23723556.2020.1819753