CD4 derived double negative T cells prevent the development and progression of nonalcoholic steatohepatitis

CD4 derived double negative T cells prevent the development and progression of nonalcoholic steatohepatitis

Hepatic inflammation contributes to the development of nonalcoholic steatohepatitis (NASH). Here, the authors show that a transfer of ex vivo generated CD4 derived double negative T cells can prevent the development and progression of NASH by suppression of inflammatory Th17 cells and M1 macrophages...

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Bibliographic Details
Main Authors: Guangyong Sun, Xinyan Zhao, Mingyang Li, Chunpan Zhang, Hua Jin, Changying Li, Liwei Liu, Yaning Wang, Wen Shi, Dan Tian, Hufeng Xu, Yue Tian, Yongle Wu, Kai Liu, Zhongtao Zhang, Dong Zhang
Format: Article
Language:English
Published: Nature Portfolio 2021-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-20941-x

Internet

https://doi.org/10.1038/s41467-021-20941-x

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