Structure-based pharmacological screening, molecular docking and dynamic simulation reveals Dexketoprofen as a repurposable drug against Alzheimer's disease
Alzheimer's disease (AD) is a progressive, irreversible, neurodegenerative disease that has a profound impact on memory, reasoning, learning, and organizational abilities. Acetylcholinesterase is one of the well-established targets for managing this disease. However, the existing acetylcholines...
Main Authors: | Ishtiaque Ahammad, Zeshan Mahmud Chowdhury, Arittra Bhattacharjee, Sheikh Sunzid Ahmed, Farzana Akter, Mohammad Uzzal Hossain, Keshob Chandra Das, Chaman Ara Keya, Md. Salimullah |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-01-01
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Series: | Informatics in Medicine Unlocked |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2352914823002265 |
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