Smooth Muscle Cells from a Rat Model of Obesity and Hyperleptinemia Are Partially Resistant to Leptin-Induced Reactive Oxygen Species Generation

The aim of this study was to evaluate the effect of leptin on reactive oxygen species’ (ROS) generation of smooth muscle cells (SMCs) from a rat model of obesity and hyperleptinemia. Obesity and hyperleptinemia were induced in rats by a sucrose-based diet for 24 weeks. ROS generation was detected by...

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Bibliographic Details
Main Authors: Ocarol López-Acosta, Magdalena Cristóbal-García, Guillermo Cardoso-Saldaña, Karla Carvajal-Aguilera, Mohammed El-Hafidi
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Antioxidants
Subjects:
Online Access:https://www.mdpi.com/2076-3921/12/3/728