Role of heparanase on hepatic uptake of intestinal derived lipoprotein and fatty streak formation in mice.

Role of heparanase on hepatic uptake of intestinal derived lipoprotein and fatty streak formation in mice.

BACKGROUND: Heparanase modulates the level of heparan sulfate proteoglycans (HSPGs) which have an important role in multiple cellular processes. Recent studies indicate that HSPGs have an important function in hepatic lipoprotein handling and processes involving removal of lipoprotein particles. PRI...

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Bibliographic Details
Main Authors: David Planer, Shulamit Metzger, Eyal Zcharia, Isaiah D Wexler, Israel Vlodavsky, Tova Chajek-Shaul
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3070732?pdf=render

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http://europepmc.org/articles/PMC3070732?pdf=render

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