The immune-opioid axis in prediabetes: predicting prediabetes with insulin resistance by plasma interleukin-10 and endomorphin-2 to kappa-opioid receptors ratio
Abstract Background Prediabetes is characterized by a hemoglobin A1c of 5.7–6.4% and fasting blood glucose of 100–125 mg/dl. A high percentage of prediabetes subjects develop type 2 diabetes mellitus in the next years. The effects of opioid peptides and their receptors, in addition to immunological...
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Format: | Article |
Language: | English |
Published: |
BMC
2021-06-01
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Series: | Diabetology & Metabolic Syndrome |
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Online Access: | https://doi.org/10.1186/s13098-021-00677-w |