Prostasin and hepatocyte growth factor B in factor VIIa generation: Serine protease knockdowns in zebrafish

Abstract Background Blood clotting in humans is initiated by the binding of tissue factor to activated coagulation factor VII (FVIIa) in the plasma. Previous studies have reported that hepsin and factor VII (FVII)‐activating protease are responsible for generating FVIIa. Objectives We aimed to ident...

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Bibliographic Details
Main Authors: Gauri Khandekar, Neha Iyer, Pudur Jagadeeswaran
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:Research and Practice in Thrombosis and Haemostasis
Subjects:
Online Access:https://doi.org/10.1002/rth2.12428