Synthesis and anti-tubercular evaluation of some novel (E)-5-(4-(benzylidene amino) phenyl)-1,3,4-oxadiazole-2-thiol derivatives

Synthesis and anti-tubercular evaluation of some novel (E)-5-(4-(benzylidene amino) phenyl)-1,3,4-oxadiazole-2-thiol derivatives

Background: Tuberculosis remains a ninth global health cause affecting millions of people. The susceptibility and resistance caused by first and second-line drugs have not changed for decades. There is a need to develop novel drugs with better pharmacological profiles. Methods: In this study, a seri...

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Bibliographic Details
Main Authors: Kuntal Das, Paramita Das, Raha Orfali, A. Ramya, Alex Joseph, Mohd. Imran, Syed Mohammed Basheeruddin Asdaq, Sultan Alshehri, Ali A. Rabaan, Mohammed Aljeldah, Bashayer M. AlShehail, Mohammed Alissa, Nawal Al Kaabi, Ameen S.S. Alwashmi, Mashael Alhajri, Mustafa A. Najim, Farhana Yasmin
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:Journal of King Saud University: Science
Subjects:
1,3,4-Oxadiazole
Docking
Simulation
M. tuberculosis
ADMET studies
Online Access:http://www.sciencedirect.com/science/article/pii/S1018364723001994

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http://www.sciencedirect.com/science/article/pii/S1018364723001994

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