Concentration of Plasmodium falciparum gametocytes in whole blood samples by magnetic cell sorting enhances parasite infection rates in mosquito feeding assays

Abstract Background Mosquito-feeding assays are important tools to guide the development and support the evaluation of transmission-blocking interventions. These functional bioassays measure the sporogonic development of gametocytes in blood-fed mosquitoes. Measuring the infectivity of low gametocyt...

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Bibliographic Details
Main Authors: Isaie J. Reuling, Will J. R. Stone, Marga van de Vegte-Bolmer, Geert-Jan van Gemert, Rianne Siebelink-Stoter, Wouter Graumans, Kjerstin Lanke, Teun Bousema, Robert W. Sauerwein
Format: Article
Language:English
Published: BMC 2017-08-01
Series:Malaria Journal
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12936-017-1959-9