A systematic two-sample and bidirectional MR process highlights a unidirectional genetic causal effect of allergic diseases on COVID-19 infection/severity

A systematic two-sample and bidirectional MR process highlights a unidirectional genetic causal effect of allergic diseases on COVID-19 infection/severity

Abstract Background Allergic diseases (ADs) such as asthma are presumed risk factors for COVID-19 infection. However, recent observational studies suggest that the assumed correlation contradicts each other. We therefore systematically investigated the genetic causal correlations between various ADs...

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Bibliographic Details
Main Authors: Xiao-tong Chen, Shuai Zhi, Xin-yu Han, Jian-wei Jiang, Guang-ming Liu, Shi-tao Rao
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Journal of Translational Medicine
Subjects:
Allergic diseases
Asthma
COVID-19 infection/severity
GWAS summary statistics
Mendelian randomization
Molecular mechanism
Online Access:https://doi.org/10.1186/s12967-024-04887-4

Internet

https://doi.org/10.1186/s12967-024-04887-4

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