The regulation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumor promotion by estradiol in female A/J mice.

Epidemiological studies indicate that women are at a higher risk developing lung cancer than men are. It is suggested that estrogen is one of the most important factors in lung cancer development in females. Additionally, cigarette smoke, and environmental pollutants, such as 2,3,7,8-tetrachlorodibe...

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Bibliographic Details
Main Authors: Rong-Jane Chen, Chu-Yung Chang, Louis W Chang, Shih-He Siao, Yuan-Soon Ho, Chih-Hsiung Wu, Ning-Ping Foo, Pinpin Lin, Ying-Jan Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3969372?pdf=render