New perspectives on the ligands and function of the killer cell immunoglobulin-like receptor KIR3DL2 in health and disease
KIR3DL2/CD158k/p140 is a 3 domain killer cell immunoglobulin-like receptor incorporating cytoplasmic ITIM motifs, expressed as a disulphide-bonded dimer. KIR3DL2 is a framework gene within the KIR locus and is highly polymorphic, with 62 allelic variants possibly coding for protein reported. KIR3D...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2012-11-01
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| Series: | Frontiers in Immunology |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00339/full |