Vascular Effects of Low-Dose ACE2 Inhibitor MLN-4760—Benefit or Detriment in Essential Hypertension?

Vascular Effects of Low-Dose ACE2 Inhibitor MLN-4760—Benefit or Detriment in Essential Hypertension?

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infects host cells through angiotensin-converting enzyme 2 (ACE2). Concurrently, the product of ACE2 action, angiotensin 1–7 (Ang 1–7), binds to Mas receptors within the cardiovascular system and provides protective effects. Therefore, it...

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Bibliographic Details
Main Authors: Andrea Berenyiova, Iveta Bernatova, Anna Zemancikova, Magdalena Drobna, Martina Cebova, Samuel Golas, Peter Balis, Silvia Liskova, Zuzana Valaskova, Katarina Krskova, Stefan Zorad, Ezgi Dayar, Sona Cacanyiova
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Biomedicines
Subjects:
essential hypertension
ACE2 inhibitor
SARS-CoV-2
Mas receptors
nitric oxide
hydrogen sulfide
Online Access:https://www.mdpi.com/2227-9059/10/1/38

Internet

https://www.mdpi.com/2227-9059/10/1/38

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