1α,25-dihydroxyvitamin D3 promotes osseointegration of titanium implant via downregulating AGEs/RAGE pathway in T2DM

Diabetes-induced advanced glycation end products (AGEs) overproduction would result in compromised osseointegration of titanium implant and high rate of implantation failure. 1α,25-dihydroxyvitamin D3 (1,25VD3) plays a vital role in osteogenesis, whereas its effects on the osseointegration and the u...

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Bibliographic Details
Main Authors: Tingting Jia, Ya-nan Wang, Dongjiao Zhang, Xin Xu
Format: Article
Language:English
Published: Bioscientifica 2018-10-01
Series:Endocrine Connections
Subjects:
Online Access:https://ec.bioscientifica.com/view/journals/ec/7/11/EC-18-0241.xml