Induced neural stem cells from distinct genetic backgrounds exhibit different reprogramming status

Induced neural stem cells from distinct genetic backgrounds exhibit different reprogramming status

Somatic cells could be directly converted into induced neural stem cells (iNSCs) by ectopic expression of defined transcription factors. However, the underlying mechanism of direct lineage transition into iNSCs is largely unknown. In this study, we examined the effect of genetic background on the di...

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Bibliographic Details
Main Authors: Sung Min Kim, Kyung Tae Lim, Tae Hwan Kwak, Seung Chan Lee, Jung Hyun Im, Sai Hali, Seon In Hwang, Dajeong Kim, Jeongho Hwang, Kee-Pyo Kim, Hak-Jae Chung, Jeong Beom Kim, Kinarm Ko, Hyung-Min Chung, Hoon Taek Lee, Hans R. Schöler, Dong Wook Han
Format: Article
Language:English
Published: Elsevier 2016-03-01
Series:Stem Cell Research
Subjects:
Genetic backgrounds
Direct conversion
Direct reprogramming
Cell fate transition
iNSCs
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506116000672

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http://www.sciencedirect.com/science/article/pii/S1873506116000672

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