Identification of growth phases and influencing factors in cultivations with AGE1.HN cells using set-based methods.

Production of bio-pharmaceuticals in cell culture, such as mammalian cells, is challenging. Mathematical models can provide support to the analysis, optimization, and the operation of production processes. In particular, unstructured models are suited for these purposes, since they can be tailored t...

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Bibliographic Details
Main Authors: Steffen Borchers, Susann Freund, Alexander Rath, Stefan Streif, Udo Reichl, Rolf Findeisen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3732265?pdf=render