Detection of SARS-CoV-2 in subcutaneous fat but not visceral fat, and the disruption of fat lymphocyte homeostasis in both fat tissues in the macaque

Detection of SARS-CoV-2 in subcutaneous fat but not visceral fat, and the disruption of fat lymphocyte homeostasis in both fat tissues in the macaque

Subcutaneous fat tissue expresses higher angiotensin-converting-enzyme 2 mRNA than visceral fat tissue and is selectively infected by SARS-Cov-2, while both fat tissues show drastic reduction in CD69 expression in T cells.

Bibliographic Details
Main Authors: Anaëlle Olivo, Romain Marlin, Thierry Lazure, Pauline Maisonnasse, Laetitia Bossevot, Christelliah Mouanga, Julien Lemaitre, Guillaume Pourcher, Stéphane Benoist, Roger Le Grand, Olivier Lambotte, Nathalie Dereuddre-Bosquet, Christine Bourgeois
Format: Article
Language:English
Published: Nature Portfolio 2022-06-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-022-03503-9

Internet

https://doi.org/10.1038/s42003-022-03503-9

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