The Role of Phosphatidylinositol-3-Kinase and AMP-Activated Kinase in the Rapid Estrogenic Attenuation of Cannabinoid-Induced Changes in Energy Homeostasis

We sought to determine the involvement of phosphatidyl inositol 3-kinase (PI3K) and AMP-activated protein kinase (AMPK) in the estrogenic antagonism of the cannabinoid regulation of energy homeostasis. Food intake and body weight were evaluated in ovariectomized female guinea pigs treated s.c. with...

Full description

Bibliographic Details
Main Authors: Edward J. Wagner, Kelly C. Peng, Garrett S. Jeffery
Format: Article
Language:English
Published: MDPI AG 2011-04-01
Series:Pharmaceuticals
Subjects:
Online Access:http://www.mdpi.com/1424-8247/4/4/630/