Somatic and terminal CB1 receptors are differentially coupled to voltage-gated sodium channels in neocortical neurons

Summary: Endogenous cannabinoid signaling is vital for important brain functions, and the same pathways can be modified pharmacologically to treat pain, epilepsy, and posttraumatic stress disorder. Endocannabinoid-mediated changes to excitability are predominantly attributed to 2-arachidonoylglycero...

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Bibliografiske detaljer
Main Authors: Luke J. Steiger, Timur Tsintsadze, Glynis B. Mattheisen, Stephen M. Smith
Format: Article
Sprog:English
Udgivet: Elsevier 2023-03-01
Serier:Cell Reports
Fag:
Online adgang:http://www.sciencedirect.com/science/article/pii/S2211124723002589