Physiochemical property space distribution among human metabolites, drugs and toxins

<p>Abstract</p> <p>Background</p> <p>The current approach to screen for drug-like molecules is to sieve for molecules with biochemical properties suitable for desirable pharmacokinetics and reduced toxicity, using predominantly biophysical properties of chemical compoun...

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Bibliographic Details
Main Authors: Ranganathan Shoba, Khanna Varun
Format: Article
Language:English
Published: BMC 2009-12-01
Series:BMC Bioinformatics