mTORC1 Regulates Flagellin-Induced Inflammatory Response in Macrophages.

Bacterial flagellin triggers inflammatory responses. Phosphoinositide 3-kinase (PI3K) and mammalian target of rapamycin (mTOR) regulate the production of pro- and anti-inflammatory cytokines that are induced by extrinsic antigens, but the function of mTORC1 in flagellin-induced inflammatory response...

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Bibliographic Details
Main Authors: Wenlei Bao, Yanfeng Wang, Yuting Fu, Xiaoyang Jia, Jiaxin Li, Nyamtsengel Vangan, Lili Bao, Huifang Hao, Zhigang Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4420466?pdf=render