Targeting AURKA in treatment of peritoneal tumor dissemination in gastrointestinal cancer

Targeting AURKA in treatment of peritoneal tumor dissemination in gastrointestinal cancer

Intraperitoneal (i.p.) tumor dissemination and the consequent malignant ascites remain unpredictable and incurable in patients with gastrointestinal (GI) cancer, and practical advances in diagnosis and treatment are urgently needed in the clinical settings. Here, we explored tumor biological and imm...

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Bibliographic Details
Main Authors: Hiroki Ozawa, Hiroshi Imazeki, Yamato Ogiwara, Hirofumi Kawakubo, Kazumasa Fukuda, Yuko Kitagawa, Chie Kudo-Saito
Format: Article
Language:English
Published: Elsevier 2022-02-01
Series:Translational Oncology
Subjects:
Gastric cancer
Ascites
Peritoneal metastasis
Treatment resistance
Immune checkpoint
Polyploidy
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523321002989

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http://www.sciencedirect.com/science/article/pii/S1936523321002989

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