A novel jamming phase diagram links tumor invasion to non-equilibrium phase separation

Summary: It is well established that the early malignant tumor invades surrounding extracellular matrix (ECM) in a manner that depends upon material properties of constituent cells, surrounding ECM, and their interactions. Recent studies have established the capacity of the invading tumor spheroids...

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Bibliographic Details
Main Authors: Wenying Kang, Jacopo Ferruzzi, Catalina-Paula Spatarelu, Yu Long Han, Yasha Sharma, Stephan A. Koehler, Jennifer A. Mitchel, Adil Khan, James P. Butler, Darren Roblyer, Muhammad H. Zaman, Jin-Ah Park, Ming Guo, Zi Chen, Adrian F. Pegoraro, Jeffrey J. Fredberg
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221012219