Locus-Specific Methylation of GSTP1, RNF219, and KIAA1539 Genes with Single Molecule Resolution in Cell-Free DNA from Healthy Donors and Prostate Tumor Patients: Application in Diagnostics

Locus-Specific Methylation of GSTP1, RNF219, and KIAA1539 Genes with Single Molecule Resolution in Cell-Free DNA from Healthy Donors and Prostate Tumor Patients: Application in Diagnostics

The locus-specific methylation of three genes (GSTP1, RNF219, and KIAA1539 (also known as FAM214B)) in the blood plasma cell-free DNA (cfDNA) of 20 patients with prostate cancer (PCa), 18 healthy donors (HDs), and 17 patients with benign prostatic hyperplasia (BPH) was studied via the MiSeq platform...

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Bibliographic Details
Main Authors: Olga Bryzgunova, Anna Bondar, Pavel Ruzankin, Petr Laktionov, Anton Tarasenko, Alexander Kurilshikov, Rostislav Epifanov, Marat Zaripov, Marsel Kabilov, Pavel Laktionov
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Cancers
Subjects:
cell-free DNA
methylation
locus-specific NGS sequencing
prostate cancer
benign prostatic hyperplasia
Online Access:https://www.mdpi.com/2072-6694/13/24/6234

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https://www.mdpi.com/2072-6694/13/24/6234

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