pH-sensing hybrid hydrogels for non-invasive metabolism monitoring in tumor spheroids

pH-sensing hybrid hydrogels for non-invasive metabolism monitoring in tumor spheroids

The constant increase in cancer incidence and mortality pushes biomedical research towards the development of in vitro 3D systems able to faithfully reproduce and effectively probe the tumor microenvironment. Cancer cells interact with this complex and dynamic architecture, leading to peculiar tumor...

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Bibliographic Details
Main Authors: Riccardo Rizzo, Valentina Onesto, Giulia Morello, Helena Iuele, Francesca Scalera, Stefania Forciniti, Giuseppe Gigli, Alessandro Polini, Francesca Gervaso, Loretta L. del Mercato
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Materials Today Bio
Subjects:
Thermoresponsive hydrogels
Silica microparticles
Ratiometric pH sensing
Tumor models
Image segmentation
Automated computational analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006423001151

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http://www.sciencedirect.com/science/article/pii/S2590006423001151

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