Casein Kinase 1 Delta Regulates Cell Proliferation, Response to Chemotherapy and Migration in Human Ovarian Cancer Cells

Casein Kinase 1 Delta Regulates Cell Proliferation, Response to Chemotherapy and Migration in Human Ovarian Cancer Cells

Casein kinase 1 delta (CK1δ) has a tumor-promoting role in different cancers and it is genetically amplified in a portion of human epithelial ovarian cancer (EOC). CK1δ is involved in pleiotropic cellular functions such as cell proliferation, DNA damage, and migration. We specifically knocked down C...

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Bibliographic Details
Main Authors: Elena Laura Mazzoldi, Anna Pastò, Elisa Ceppelli, Giorgia Pilotto, Vito Barbieri, Alberto Amadori, Simona Pavan
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Oncology
Subjects:
epithelial ovarian cancer
casein kinase 1 delta
cell proliferation
carboplatin
cell migration
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.01211/full

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https://www.frontiersin.org/article/10.3389/fonc.2019.01211/full

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