Distinct immunological and molecular signatures underpinning influenza vaccine responsiveness in the elderly

Seasonal influenza vaccination is an important strategy to prevent serious disease in the elderly, but individual responsiveness to vaccination widely vary. Here authors establish, with an array of state-of-the art methods, the major immunological parameters that distinguish vaccine recipients devel...

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Bibliographic Details
Main Authors: Peggy Riese, Stephanie Trittel, Manas K. Akmatov, Marcus May, Jana Prokein, Thomas Illig, Christoph Schindler, Birgit Sawitzki, Yassin Elfaki, Stefan Floess, Jochen Huehn, Adrian J. Błażejewski, Till Strowig, Esteban A. Hernandez-Vargas, Robert Geffers, Bowen Zhang, Yang Li, Frank Pessler, Carlos A. Guzmán
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-34487-z