Ginkgo biloba L. Prevents Hypobaric Hypoxia–Induced Spatial Memory Deficit Through Small Conductance Calcium-Activated Potassium Channel Inhibition: The Role of ERK/CaMKII/CREB Signaling

Ginkgo biloba L. Prevents Hypobaric Hypoxia–Induced Spatial Memory Deficit Through Small Conductance Calcium-Activated Potassium Channel Inhibition: The Role of ERK/CaMKII/CREB Signaling

Hypobaric hypoxia (HH) is a stressful condition, which is more common at high altitudes and can impair cognitive functions. Ginkgo biloba L. leaf extract (GBE) is widely used as herbal medicine against different disorders. Its ability to improve cognitive functions, reduce oxidative stress, and prom...

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Bibliographic Details
Main Authors: Neetu Kushwah, Vishal Jain, Manisha Kadam, Rahul Kumar, Aastha Dheer, Dipti Prasad, Bhuvnesh Kumar, Nilofar Khan
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Pharmacology
Subjects:
Gingko biloba L. leaf extract
SK channels
hippocampus
neurodegeneration
memory
hypobaric hypoxia
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.669701/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.669701/full

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