Chitopentaose inhibits hepatocellular carcinoma by inducing mitochondrial mediated apoptosis and suppressing protective autophagy

Chitopentaose inhibits hepatocellular carcinoma by inducing mitochondrial mediated apoptosis and suppressing protective autophagy

Abstract Hepatocellular carcinoma (HCC) is one of the most prevalent and deadliest cancers. In this study, the anti-tumor effect of singular degree of polymerization (DP) chitooligosaccharides (COS) (DP 2–5) and the underlay molecular mechanisms were investigated on HCC cell line HepG2. MTT assay sh...

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Bibliographic Details
Main Authors: Chunfeng Zhu, Mengyao Zhao, Liqiang Fan, Xuni Cao, Quanming Xia, Jiachun Zhou, Hao Yin, Liming Zhao
Format: Article
Language:English
Published: SpringerOpen 2021-01-01
Series:Bioresources and Bioprocessing
Subjects:
Chitooligosaccharides
Singular DP
HCC
Apoptosis
Autophagy
Online Access:https://doi.org/10.1186/s40643-020-00358-y

Internet

https://doi.org/10.1186/s40643-020-00358-y

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